1160656-28-9

Upstream product

• 99314-44-0 (3-methyloxetan-3-yl)methyl 4-methylbenzenesulfonate 
• 1761-61-1 5-bromosalicyclaldehyde 

Downstream Products

• 1162669-80-8 E/Z-3-[5-bromo-2-(3-methyl-oxetan-3-ylmethoxy)-benzylidene]-6-chloro-1,3-dihydro-indol-2-one 

Relevant academic research and scientific papers

Spiroindolinone Derivatives

There are provided compounds of the formula and pharmaceutically acceptable salts and esters and enantiomers thereof wherein W, X, X′, Y, V, V′, A, B and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

SPIROINDOLINONE DERIVATIVES

There are provided compounds of the formula and pharmaceutically acceptable salts and esters thereof wherein W, V, X, Y, A, R and R' are as described herein. The compounds are useful as anticancer agents.