116076-84-7Relevant academic research and scientific papers
Copper-Catalyzed Ring-Opening Radical Trifluoromethylation of Cycloalkanone Oximes
Liu, Zhonglin,Shen, Haigen,Xiao, Haiwen,Wang, Zhentao,Zhu, Lin,Li, Chaozhong
, p. 5201 - 5205 (2019)
The copper-catalyzed ring-opening C-trifluoromethylation of cycloalkanone oximes with Zn(CF3)2 complexes is described. The reaction proceeds in dichloromethane under mild conditions, providing an efficient and general entry to γ- or
Polar Effects in Radical Addition Reactions: Borderline Cases
Giese, Bernd,He, Jianing,Mehl, Wolf
, p. 2063 - 2066 (2007/10/02)
Methyl radicals substituted by one ester or nitrile group are on the borderline between nucleophilic and electrophilic behavior.In addition reactions of these borderline radicals to styrenes, polar effects of both, electron-withdrawing and electron-donating substituents at the alkene, increase the rates.But these polar effects are smaller compared to those of nucleophilic or electrophilic radicals.In consequence, the stability of the radicals formed during the addition of the borderline radicals to styrenes are of major importance for the rate of the reaction.
