1160857-81-7

Basic information

• Product Name: 5-chloro-1-(cyclohexylmethyl)-3-phenylpyrazin-2(1H)-one
• Synonyms: 5-chloro-1-(cyclohexylmethyl)-3-phenylpyrazin-2(1H)-one
• CAS NO: 1160857-81-7
• Molecular Weight: 302.804
• Mol File: 1160857-81-7.mol

Chemical Properties

• CAS DataBase Reference: 5-chloro-1-(cyclohexylmethyl)-3-phenylpyrazin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-1-(cyclohexylmethyl)-3-phenylpyrazin-2(1H)-one(1160857-81-7)
• EPA Substance Registry System: 5-chloro-1-(cyclohexylmethyl)-3-phenylpyrazin-2(1H)-one(1160857-81-7)

Safety Data

• Hazardous Substances Data: 1160857-81-7(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 2996-92-1 phenyl trimethylsiloxane 

Relevant articles and documents

Palladium-catalyzed desulfitative C-C cross-coupling reaction of (hetero)aryl thioesters and thioethers with arylsiloxanes

The first desulfitative Hiyama-type cross-coupling protocol is reported and exemplified by the synthesis of substituted 5-chloro-3-arylpyrazinones. The method has also been successfully applied for the arylation of other (hetero)aryl thioethers and thioes

Mild room-temperature palladium-catalyzed C3-arylation of 2(1H)-pyrazinones via a desulfitative kumada-type cross-coupling reaction

(Chemical Equation Presented) An efficient desulfitative Kumada-type cross-coupling protocol is reported for the C3-arylation of 5-chloro-3- (phenylsulfanyl)pyrazin-2(1H)-ones. The method has also been successfully extended to the arylation of some (heter