1160922-20-2Relevant academic research and scientific papers
First generation 5-vinyl-3-pyridinecarbonitrile PKCθ inhibitors
Niu, Chuansheng,Boschelli, Diane H.,Tumey, L. Nathan,Bhagirath, Niala,Subrath, Joan,Shim, Jaechul,Wang, Yan,Wu, Biqi,Eid, Clark,Lee, Julie,Yang, Xiaoke,Brennan, Agnes,Chaudhary, Divya
scheme or table, p. 5829 - 5832 (2010/04/28)
A series of 5-vinyl-3-pyridinecarbonitriles were synthesized and evaluated as PKCθ inhibitors. The systematic optimization of 4-[(4-methyl-1H-indol-5-yl)amino]-5-[(E)-2-phenylvinyl]-3-pyridinecarbon itrile 3 resulted in the identification of compound 23e
