1160924-36-6

Basic information

• Product Name: 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine
• Synonyms: 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine
• CAS NO: 1160924-36-6
• Molecular Formula: C11H16BrN3
• Molecular Weight: 270
• Mol File: 1160924-36-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine(1160924-36-6)
• EPA Substance Registry System: 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine(1160924-36-6)

Safety Data

• Hazardous Substances Data: 1160924-36-6(Hazardous Substances Data)

Usage

General Description

1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine is a chemical compound with the molecular formula C13H18BrN3. It is a derivative of piperazine and contains a piperazine ring with a methyl group at the 4-position and a 5-bromopyridin-3-yl)methyl group. 1-((5-bromopyridin-3-yl)methyl)-4-methylpiperazine is commonly used in medicinal chemistry as a building block for the synthesis of various pharmaceutical drugs. It may also have biological activities and is being studied for its potential therapeutic uses in the treatment of various medical conditions. Additionally, it is important to handle this chemical with care, as it can be hazardous if not handled properly.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 113118-81-3 5-bromopyridine-3-carbaldehyde 

Relevant articles and documents

METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS

This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

ARYL INDOLE DERIVATIVES

A novel aryl indole derivative is provided that is effective as a preventive or remedy for various diseases. A compound represented by a formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R1 is a hydrogen atom, halogen, C1-6alkyl, haloC1-6alkyl, C1-6alkyloxy, or haloC1-6alkyloxy; R2 represents C1-6alkyl or haloC1-6alkyl; R3 represents a hydrogen atom, C1-6alkyl, or haloC1-6alkyl; and Ar represents an aryl or heteroaryl, wherein the aryl or the heteroaryl may be substituted with 1 to 3 substituents such as halogen, C1-6alkyl, haloC1-6alkyl, and C1-6alkyloxy.

PYRIMIDINE DERIVATIVES USED AS ITK INHIBITORS

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular ltk activity.