116097-54-2

Basic information

• Product Name: Carbonic acid, (5-fluoro-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinyl)methyl phenylmethyl ester
• CAS NO: 116097-54-2
• Molecular Formula: C13H11FN2O5
• Molecular Weight: 294.239
• Mol File: 116097-54-2.mol

Chemical Properties

• CAS DataBase Reference: Carbonic acid, (5-fluoro-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinyl)methyl phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid, (5-fluoro-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinyl)methyl phenylmethyl ester(116097-54-2)
• EPA Substance Registry System: Carbonic acid, (5-fluoro-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinyl)methyl phenylmethyl ester(116097-54-2)

Safety Data

• Hazardous Substances Data: 116097-54-2(Hazardous Substances Data)

Upstream product

• 74179-14-9 N¹,N³-bis(hydroxymethyl)-5-fluorouracil 
• 116097-55-3 1,3-bis-(benzyloxycarbonyloxymethyl)-5-fluorouracil 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 118004-30-1 Carbonic acid 3-allyl-5-fluoro-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl ester benzyl ester 
• 118004-31-2 Carbonic acid benzyl ester 5-fluoro-3-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl ester 
• 118004-29-8 (3-Benzyloxycarbonyloxymethyl-5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetic acid ethyl ester 
• 118004-27-6 Carbonic acid benzyl ester 5-fluoro-3-methoxymethyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl ester 
• 118004-32-3 Carbonic acid benzyl ester 3-benzyl-5-fluoro-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl ester 
• 118004-28-7 Carbonic acid benzyl ester 3-butyl-5-fluoro-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl ester 

Relevant articles and documents

SELECTIVE SYNTHESIS OF 1-ALKOXYCARBONYLOXYMETHYL-5-FLUOROURACILS VIA 1,3-BIS(HYDROXYMETHYL)-5-FLUOROURACIL

Esterification of 1,3-bis(hydroxymethyl)-5-fluorouracil with various alkyl chloroformates in the presence of tert- or hindered sec-alkylamine selectively gave potentially antitumor active 1-alkoxycarbonyloxymethyl-5-fluorouracils in moderate to good yield

Application of the Benzyloxycarbonyloxymethyl Moiety to a Protective Group of 5-Fluoroacil. Selective Alkylation of Amide Nitrogen of the Uracil Ring

Selective alkylation of 5-fluorouracil using the benzoyloxycarbonyloxymethyl moiety as a protective group of amide nitrogen of the uracil ring is described.Protection, alkylation and deprotection were carried out in high yields.