1161-94-0 Usage
Uses
Used in Pharmaceutical Industry:
Phenamil Methanesulfonate is used as a pharmaceutical agent for inducing differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte.
Used in Cell Biology Research:
Phenamil Methanesulfonate is used as a stimulant for adipocyte differentiation in 3T3 cells to test its effect on lateral flagella expression in Vibrio shilonii.
Used in Nanoparticle Preparation:
Phenamil Methanesulfonate is used in nanoparticle preparation to test its effect on osteo/odontoblastic differentiation.
Biochem/physiol Actions
Phenamil is an inducer of peroxisome proliferator-activated receptor γ (PPARγ) and inhibits diamine oxidase. By favoring tribbles homolog 3 (Trb3) expression, phenamil holds therapeutic potential to treat pulmonary artery hypertension (PAH) and idiopathic PAH. It is also a bone morphogenetic protein (BMP) activator, which favors osteogenesis and odontogenesis of stem cells.
Check Digit Verification of cas no
The CAS Registry Mumber 1161-94-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,6 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1161-94:
(6*1)+(5*1)+(4*6)+(3*1)+(2*9)+(1*4)=60
60 % 10 = 0
So 1161-94-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21)/p+1
