1161005-04-4

Basic information

• Product Name: Methyl 3-(2-(trifluoroMethyl)-1H-indol-3-yl)propanoate
• Synonyms: Methyl 3-(2-(trifluoroMethyl)-1H-indol-3-yl)propanoate
• CAS NO: 1161005-04-4
• Molecular Formula: C13H12F3NO2
• Molecular Weight: 271
• Mol File: 1161005-04-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 3-(2-(trifluoroMethyl)-1H-indol-3-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-(2-(trifluoroMethyl)-1H-indol-3-yl)propanoate(1161005-04-4)
• EPA Substance Registry System: Methyl 3-(2-(trifluoroMethyl)-1H-indol-3-yl)propanoate(1161005-04-4)

Safety Data

• Hazardous Substances Data: 1161005-04-4(Hazardous Substances Data)

Upstream product

• 253605-13-9 methyl 3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionate 
• 5548-09-4 Methyl indole-3-propionate 
• 887144-94-7 Togni's reagent II 
• 100-63-0 phenylhydrazine 
• 1161004-61-0 methyl 6,6,6-trifluoro-5-oxohexanoate 

Relevant articles and documents

Rapid trifluoromethylation of indole derivatives

Rapid trifluoromethylation of indole derivatives was achieved using trimethylsilyltriflate as the catalyst. Good to high yields were observed within only 5 min at room temperature. This reaction system is able to provide not only the mono-trifluoromethyla

Direct aromatic C-H trifluoromethylation via an electron-donor-acceptor complex

A novel electron-donor-acceptor (EDA) complex-mediated direct C-H trifluoromethylation of arenes with Umemoto's reagent has been developed. This transformation has been enabled by an unprecedented EDA complex formed by Umemoto's reagent and an amine, whic

p-TsOH promoted Fischer indole synthesis of multi-substituted 2-trifluoromethyl indole derivatives

A p-TsOH promoted one-pot synthesis of multi-substituted 2-trifluoromethyl indole derivatives, for instance, 2-trifluoromethyl-3-phenylindoles, 2-trifluoromethyl-indole-3-propanoates, and 2-trifluoromethyl-indole-3-butanoates from reactions of 1,1,1-trifluoro-3-phenylacetone and simply prepared ω-trifluoromethyl substituted δ and ε-ketoesters with arylhydrazines via Fischer indole synthesis has been developed.