1161015-95-7

Basic information

• Product Name: {[[1-(2,2-diethoxyethylcarbamoyl)-3-methylbutyl]-(2,4-dimethoxybenzyl)carbamoyl]methyl}carbamic acid benzyl ester
• CAS NO: 1161015-95-7
• Molecular Weight: 587.714
• Mol File: 1161015-95-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {[[1-(2,2-diethoxyethylcarbamoyl)-3-methylbutyl]-(2,4-dimethoxybenzyl)carbamoyl]methyl}carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {[[1-(2,2-diethoxyethylcarbamoyl)-3-methylbutyl]-(2,4-dimethoxybenzyl)carbamoyl]methyl}carbamic acid benzyl ester(1161015-95-7)
• EPA Substance Registry System: {[[1-(2,2-diethoxyethylcarbamoyl)-3-methylbutyl]-(2,4-dimethoxybenzyl)carbamoyl]methyl}carbamic acid benzyl ester(1161015-95-7)

Safety Data

• Hazardous Substances Data: 1161015-95-7(Hazardous Substances Data)

Upstream product

• 20781-20-8 2,4-Dimethoxybenzylamine 
• 15586-32-0 1,1-diethoxy-2-isocyanoethane isocyanide 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 590-86-3 isovaleraldehyde 

Downstream Products

• 1161015-88-8 {[3-methyl-1-(2-oxoethylcarbamoyl)butylcarbamoyl]methyl}carbamic acid benzyl ester 

Relevant articles and documents

A new and general method for the synthesis of tripeptide aldehydes based on the multi-component Ugi reaction

Tripeptide aldehydes, such as Z-Leu-Leu-Leu-H (MG-132), are an important class of compounds due to their biological activity. A new, general method for the synthesis of tripeptide aldehydes based on the multi-component Ugi reaction was developed. A careful choice of isocyanides makes it possible to obtain tripeptide precursors whose functionalization led to target structures. This method can be used for the preparation of tripeptide aldehydes with non-natural amino acid side chains.