116121-47-2Relevant academic research and scientific papers
4- AND 5-HYDROXYLAMINOTHIAZOLIDINE-2-THIONES. REARRANGEMENT OF THE CARBAMOYL DERIVATIVES TO 4- AND 5-UREIDOTHIAZOLIDIN-2-ONES
Orlova, T. I.,Epshtein, S. P.,Rukasov, A. F.,Tashchi, V. P.,Putsykin, Yu. G.
, p. 1352 - 1356 (2007/10/02)
The carbamoylation of 4- and 5-hydroxylaminothiazolidine-2-thiones by methyl and 3,4-dichlorophenyl isocyanates leads to the corresponding hydroxyureas, which rearrange to 4- and 5-ureidothiazolidin-2-ones on heating in the presence of a base.Under these conditions, the hydroxyurea based on 5-hydroxylaminothiazolidin-2-one is converted to 5-ureidooxazolidin-2-one.
