116129-80-7Relevant articles and documents
Use of propargyl glycine amino propargyl diol compounds for inhibiting plasma renin activity
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Page column 17, (2010/01/30)
Compounds characterized generally as propargyl glycine amino propargyl diol derivatives are useful for treatment of a disorder mediated by inhibiting plasma renin activity. Compounds of particular interest are those of Formula I wherein A is selected from
USE OF ETHYNYL ALANINE AMINO DIOL COMPOUNDS FOR TREAMENT OF OPHTHALMIC DISORDERS
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, (2008/06/13)
Compounds characterized generally as ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of ophthalmic disorders. Compounds of particular interest are those of Formula I STR1 wherein A is selected from CO and SO 2 where
Imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
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, (2008/06/13)
Compounds characterized generally as imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I STR1 wher