116140-31-9Relevant academic research and scientific papers
Derives alkyles et aryles de l'acide nipecotique: synthese et appreciation de l'activite inhibitrice de la capture du GABA en fonction de parametres conformationnels et de biodisponibilite
Lapuyade, Gerard,Schlewer, Gilbert,N'Goka, Victor,Vernieres, Jean-Claude,Chambon, Jean-Pierre,et al.
, p. 383 - 392 (2007/10/02)
Alkyl and aryl derivatives of nipecotic acid: synthesis and inhibition of GABA uptake as a function of conformational parameters and bioavailability.Analogs of nipecotic acid, substituted at positions 2, 3, 4, 5, or 6 with a methyl or phenyl group were pr
Synthesis of Phenyl- and Benzyl-Substituted Pyrrolidines and of a Piperidine by Intramolecular C-Alkylation. Synthons for Tricyclic Skeletons
Achini, Roland
, p. 2203 - 2218 (2007/10/02)
The construction of new or novelly functionalized annulated and bridged tricyclic compounds by two consecutive C,C-bond formations (a and b in 1a, Scheme 1) is described.In a first step, Chloroalkyl-substituted aminonitriles yielded pyrrolidines 8, 15a, 1
