1161415-82-2Relevant academic research and scientific papers
Probes for narcotic receptor mediated phenomena. 38.1 An expeditious synthesis of rac-cis-4a-ethyl-2-methyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin -6-ol and rac-cis-2-methyl-4a-phenethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyr idin-6
Iyer, Malliga R.,Deschamps, Jeffrey R.,Jacobson, Arthur E.,Rice, Kenner C.
experimental part, p. 1061 - 1072 (2009/12/26)
A high-yielding five-step synthesis of cis-benzofuropyridin-6-ols provided an improved route to compounds with low to subnanomolar affinity at opioid receptors and high antinociceptive potency. This synthesis provided the known rac-cis-4a-ethyl-2-methyl-1
