116159-02-5Relevant academic research and scientific papers
REDOX-DEPENDENT COMPLEXATION ABILITY OF FLAVIN-HOSTS IN AQOEOUS SOLUTION
Seward, Eileen,Diederich, Francois
, p. 5111 - 5114 (1987)
The synthesis of the novel macrocyclic host 1 incorporating an isoalloxazine moiety as model for active sites of flavoenzymes is described.The complexation between oxidized and reduced flavin-host and aromatic guests is analyzed in aqueous solution.
Redox-dependent binding ability of a flavin cyclophane in aqueous solution: Hydrophobic stacking versus cavity-inclusion complexation
Seward,Hopkins,Sauerer,Tam,Diederich
, p. 1783 - 1790 (1990)
A novel water-soluble flavinophane (1) and a nonmacrocyclic isoalloxazine comparison compound 3 were prepared. The host-guest binding interactions and the self-association of these flavin derivatives were investigated in an aqueous borate buffer at pH 10
