116168-96-8

Basic information

• Product Name: Benzenepropanenitrile, a-(4-morpholinylmethylene)-4-(phenylmethoxy)-
• CAS NO: 116168-96-8
• Molecular Formula: C21H22N2O2
• Molecular Weight: 334.418
• Mol File: 116168-96-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanenitrile, a-(4-morpholinylmethylene)-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanenitrile, a-(4-morpholinylmethylene)-4-(phenylmethoxy)-(116168-96-8)
• EPA Substance Registry System: Benzenepropanenitrile, a-(4-morpholinylmethylene)-4-(phenylmethoxy)-(116168-96-8)

Safety Data

• Hazardous Substances Data: 116168-96-8(Hazardous Substances Data)

Upstream product

• 4542-47-6 3-Morpholin-4-yl-propionitrile 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 49873-11-2 5-(4-benzyloxy-benzyl)-pyrimidine-2,4-diamine 
• 30077-74-8 3-anilino-2-<4-(benzyloxy)benzyl>acrylonitrile 

Relevant articles and documents

Synthesis and antimycobacterial effects of some lipophilic substituted 2,4-diamino-5-benzylpyrimidines

2,4-Diamino-5-benzylpyrimidines 1-23 with lipophilic substitution in the benzylic moiety were synthesized by the morpholino-anilino-procedure. Their effects against various mycobacteria were verified by MIC (minimum inhibitory concentration) in whole cells and I50-measurements in whole cell and cell-free systems. Especially the substances 7-12 are strong inhibitors of some atypical mycobacterial strains which are sometimes associated with tuberculosis in the elderly and with AIDS. They might be promising candidates for therapy.