116169-42-7

Basic information

• Product Name: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-3-phenyl-1-pyrrolid inyl)-1-cyclopropyl-6,8-difluoro-4-oxo-
• Synonyms: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-3-phenyl-1-pyrrolid inyl)-1-cyclopropyl-6,8-difluoro-4-oxo-;3-Quinolinecarboxylic acid, 7-(3-aMino-3-phenyl-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-
• CAS NO: 116169-42-7
• Molecular Formula: C₂₃H₂₁F₂N₃O₃
• Molecular Weight: 425.43
• Mol File: 116169-42-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 630°Cat760mmHg
• Flash Point: 334.8°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 9.76E-17mmHg at 25°C
• Refractive Index: 1.673
• PKA: 6.40±0.50(Predicted)
• CAS DataBase Reference: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-3-phenyl-1-pyrrolid inyl)-1-cyclopropyl-6,8-difluoro-4-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-3-phenyl-1-pyrrolid inyl)-1-cyclopropyl-6,8-difluoro-4-oxo-(116169-42-7)
• EPA Substance Registry System: 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-3-phenyl-1-pyrrolid inyl)-1-cyclopropyl-6,8-difluoro-4-oxo-(116169-42-7)

Safety Data

• Hazardous Substances Data: 116169-42-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H21F2N3O3/c24-17-10-15-19(28(14-6-7-14)11-16(21(15)29)22(30)31)18(25)20(17)27-9-8-23(26,12-27)13-4-2-1-3-5-13/h1-5,10-11,14H,6-9,12,26H2,(H,30,31)

Upstream product

• 116169-48-3 3-phenyl-3-pyrrolidinamine 
• 94695-52-0 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinolin-3-carboxylic acid 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 124562-91-0 3-phenyl-1-(phenylmethyl)-3-pyrrolidinecarboxylic acid hydrochloride 
• 124562-92-1 3-phenyl-1-(phenylmethyl)-3-pyrrolidinecarbamic butyl ester 
• 124562-89-6 3-phenyl-1-(phenylmethyl)-3-pyrrolidinecarboxylic acid methyl ester 
• 124563-09-3 (±)-1-benzyl-3-phenyl-pyrrolidin-3-amine 
• 1865-29-8 2-phenyl-acrylic acid methyl ester 

Relevant articles and documents

New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- or 3,4-disubstituted-1-pyrrolidinyl)quinoline-3-carboxylic acids

A series of 7-(3-amino- or 3-aminomethyl-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro- 4-oxo-3-quinolinecarboxylic acids was synthesized and tested for antibacterial activity. Unique to these quinolones was the presence of a methyl or phenyl gro

Disubstituted-7-pyrrolidinonaphthyridine antibacterial agents

Disubstituted 7-pyrrolidinoquinoline- and -naphthyridine-3-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.