116173-67-2 Usage
Description
β-Alanine-2,2,3,3-d4 is a naturally occurring beta amino acid that is labeled with four deuterium atoms. It is formed in vivo by the degradation of dihydrouracil and carnosine. β-Alanine is also the rate-limiting precursor of carnosine, and supplementation with β-Alanine-2,2,3,3-d4 increases the concentration of carnosine in muscles.
Uses
Used in Pharmaceutical Industry:
β-Alanine-2,2,3,3-d4 is used as a stable isotope-labeled compound for studying the metabolism and pharmacokinetics of β-alanine and its related compounds. The deuterium labeling allows for easier detection and tracking of the compound in biological systems, providing valuable insights into its metabolic pathways and potential therapeutic applications.
Used in Sports Nutrition Industry:
β-Alanine-2,2,3,3-d4 is used as a supplement to increase the concentration of carnosine in muscles. Carnosine has been shown to buffer hydrogen ions and delay the onset of muscle fatigue during high-intensity exercise. By supplementing with β-Alanine-2,2,3,3-d4, athletes can improve their performance and reduce muscle soreness after intense workouts.
Used in Research Applications:
β-Alanine-2,2,3,3-d4 is used as a research tool in various scientific studies. The deuterium labeling of the compound makes it an ideal candidate for investigating the role of β-alanine in various biological processes, such as neurotransmitter synthesis, immune function, and antioxidant defense. Additionally, it can be used to study the effects of β-alanine supplementation on cognitive function and stress response.
Check Digit Verification of cas no
The CAS Registry Mumber 116173-67-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,1,7 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 116173-67:
(8*1)+(7*1)+(6*6)+(5*1)+(4*7)+(3*3)+(2*6)+(1*7)=112
112 % 10 = 2
So 116173-67-2 is a valid CAS Registry Number.
116173-67-2Relevant articles and documents
Syntheses of 2H-labelled dihydropyrimidinediones and their metabolites
Heinkele, Georg,Hofmann, Ute,Opitz, Joachim,Muerdter, Thomas E.
, p. 7 - 11 (2007/10/03)
Starting with uracil or thymine, [5,5,6,6-2H4]-dihydrouracil and [5,6,6,α,α,α,-2H6]-dihydrothymine were synthesised in high yields by catalytic deuteriation. Subsequent hydrolyses resulted in the corresponding β-ureidoalkanoic acids and β-aminoacids.
