1161749-07-0Relevant academic research and scientific papers
Selective inhibitors of plasmepsin II of Plasmodium falciparum on the basis of pepstatin
Rumsh,Mikhailova,Mikhura,Prudchenko,Chikin,Mikhaleva,Kaliberda,Dergousova,Mel'Nikov,Formanovskii
, p. 660 - 667 (2008)
A number of new inhibitors of plasmepsin II (PlmII) Plasmodium falciparum, which was one of the key factors of survival of malarial parasite, was synthesized. The inhibitors were analogues of pepstatin with different substitutions for the alanine residue.
