1161833-78-8 Usage
General Description
1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-6-methoxy- is a chemical compound with the molecular formula C11H13NO3. It is a derivative of isoquinoline and has a tetrahydro-6-methoxy substitution on the 1,2,3,4 positions of the isoquinoline ring. 1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-6-methoxy- is used in the pharmaceutical industry as a building block for the synthesis of various biologically active compounds. It has been reported to have potential antifungal and anticancer activities, making it an important molecule for drug discovery and development. Additionally, 1-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-6-methoxy- has also been studied for its neuroprotective and anticonvulsant properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1161833-78-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,1,8,3 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1161833-78:
(9*1)+(8*1)+(7*6)+(6*1)+(5*8)+(4*3)+(3*3)+(2*7)+(1*8)=148
148 % 10 = 8
So 1161833-78-8 is a valid CAS Registry Number.
1161833-78-8Relevant articles and documents
Efficient dynamic kinetic resolution method for the synthesis of enantiopure 6-hydroxy- and 6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid
Forró, Enik?,Megyesi, Rita,Paál, Tihamér A.,Fül?p, Ferenc
, p. 1213 - 1216 (2016)
Enantiomeric 6-hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (ee >99%), useful in the synthesis of modulators of nuclear receptors, including liver X receptor and its analogue 6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (ee >99%), a source of the above enantiomer was synthesized through Candida antarctica lipase B-catalysed dynamic kinetic hydrolysis of the corresponding 1,2,3,4-tetrahydroisoquinoline-1-carboxylic esters (±)-4·HCl and (±)-5. (R)-Selective hydrolysis in both organic solvents and an aqueous NH4OAc buffer at pH 8.5 was observed and the amino acids were obtained in good chemical yields (>87%).
