1161931-71-0

Basic information

• Product Name: (2R,4R)-1-BOC-2-hydroxyMethyl-4-aMino Pyrrolidine-HCl
• Synonyms: (2R,4R)-1-BOC-2-hydroxyMethyl-4-aMino Pyrrolidine-HCl;(2R,4R)-1-Boc-2-HydroxyMethyl-4-aMinopyrrolidine hydrochloride;1-Pyrrolidinecarboxylic acid, 4-aMino-2-(hydroxyMethyl)-, 1,1-diMethylethyl ester, (2R,4R)-;(2R,4R)-tert-Butyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate hydrochloride;tert-butyl (2R,4R)-4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate;-1-Boc-2-Hydroxymethyl-4-aminopyrrolidine hydrochloride
• CAS NO: 1161931-71-0
• Molecular Formula: C10H21ClN2O3
• Molecular Weight: 252.73834
• Mol File: 1161931-71-0.mol

Chemical Properties

• Boiling Point: 323.3±27.0 °C(Predicted)
• Appearance: /
• Density: 1.120±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.77±0.10(Predicted)
• CAS DataBase Reference: (2R,4R)-1-BOC-2-hydroxyMethyl-4-aMino Pyrrolidine-HCl(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-1-BOC-2-hydroxyMethyl-4-aMino Pyrrolidine-HCl(1161931-71-0)
• EPA Substance Registry System: (2R,4R)-1-BOC-2-hydroxyMethyl-4-aMino Pyrrolidine-HCl(1161931-71-0)

Safety Data

• Hazardous Substances Data: 1161931-71-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
(2R,4R)-1-BOC-2-hydroxymethyl-4-amino Pyrrolidine-HCl is used as a building block for the synthesis of more complex molecules in the pharmaceutical industry. Its unique structure and functional groups make it a valuable intermediate in the development of new drugs and therapeutic agents. The BOC protective group can be selectively removed under mild conditions, allowing for further functionalization and modification of the molecule, while the hydroxymethyl and amino groups provide opportunities for conjugation and interaction with other molecules. This versatility makes it a promising candidate for various applications in drug discovery and medicinal chemistry.

Upstream product

• 1161931-70-9 (2S,4R)-tert-butyl 4-azido-2-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 1245725-18-1 (2R,4R)-4-(4-bromo-2-nitro-phenylamino)-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

MINERALOCORTICOID RECEPTOR ANTAGONIST AND METHODS OF USE

The present invention provides a compound of the formula: Compound (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising Compound (I) in combination with a suitable carrier, diluent, or excipient; and methods for treati

MINERALOCORTICOID RECEPTOR ANTAGONISTS AND METHODS OF USE

The present invention provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I) in combination with a suitable carrier, diluent, or excipient; and methods for treating physiological disorders, particularly congestive heart failure, hypertension, diabetic nephropathy, or chronic kidney disease, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt thereof.