116199-87-2

Basic information

• Product Name: 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester
• Synonyms: 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester;3-Isopropenyl-2-oxo-;ethyl 4-(2-oxo-3-(prop-1-en-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanoate
• CAS NO: 116199-87-2
• Molecular Formula: C16H20N2O3
• Molecular Weight: 288.3416
• Product Categories: Aliphatics;Aromatics;Heterocycles;Aliphatics, Aromatics, Heterocycles
• Mol File: 116199-87-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 415.6±47.0 °C(Predicted)
• Appearance: /
• Density: 1.154±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 0.68±0.20(Predicted)
• CAS DataBase Reference: 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester(116199-87-2)
• EPA Substance Registry System: 3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester(116199-87-2)

Safety Data

• Hazardous Substances Data: 116199-87-2(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Oil

Uses

3-Isopropenyl-2-oxo-1-benzimidazolinebutyric Acid Ethyl Ester (cas# 116199-87-2) is a compound useful in organic synthesis.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 52099-72-6 1,3-dihydro-1-(1-methylethenyl)-2H-benzimidazol-2-one 
• 2969-81-5 Ethyl 4-bromobutyrate 

Downstream Products

• 1019769-22-2 (6S,7S)-7-hydroxy-6-{[(S)-3-(2-hydroxyphenyl)-1-methylpropyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 
• 1019768-88-7 (6R,7R)-7-hydroxy-6-{[(R)-3-(2-hydroxyphenyl)-1-methylpropyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 

Relevant articles and documents

Synthesis of imidazobenzazepinthiones: A new series of HIV-1 reverse transcriptase inhibitors

A general route to a series of novel imidazobenzazepines that are 'carba' analogs of the TIBO class of non-nucleoside HIV-1 reverse transcriptase inhibitors has been developed. A pair of allyl side-chain containing compounds were found to have significant HIV-1 inhibitory activity.

BENZAZEPIN-2(1H)-ONE DERIVATIVES

Compounds of formula (I) and pharmaceutically acceptable salts thereof are agonists at the beta-2 adrenoceptor. They are useful as feed additives for livestock animals.

Novel 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-j-k][1]-benzazepin-2-(1H)-one

Novel 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,l-j-k][1]-benzazepin-2-(1H)-one derivatives of the formula STR1 wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms optionally substituted with a hydroxyl, aryl and aryloxy of 6 to 10 carbon atoms, cycloalkyl of 3 to 7 carbon atoms optionally interrupted with a heteroatom optionally substituted with alkyl of 1 to 4 carbon atoms and the wavy lines indicates that the 7-OH and 6-amino have the trans configuration and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anti-hypertensive and hypotensive activity and vasodilatatory activity and their preparation.