116204-34-3Relevant academic research and scientific papers
Hydrolysis of (Z)-2-alkoxy-3-arylpropenals as a short-cut to benzylglyoxals
Keiko, Natalia A.,Vchislo, Nadezhda V.,Verochkina, Ekaterina A.,Chuvashev, Yurii A.,Larina, Lyudmila I.
, p. 431 - 433 (2016)
Hydrolysis of the C=C bond in 2-alkoxy-3-aryl(hetaryl)-propenals, depending upon substituents in the molecule, can proceed according to Markovnikov or Michael rule or with heterolytic opening of the cycle (in the case of 2-alkoxy-3-furylpropenal). Hydrolysis of 3-phenyl substituted alkoxypropenals bearing electron-withdrawing substituents (Cl, NO2) in the p-position has allowed a method for the preparation of corresponding benzylglyoxals (stable in enol form) to be developed.
A Simple and Direct Synsthesis of α-Hydroxy Unsaturated Adehydes from α-Cyano- α-Hydroxymethyl Epoxides
Khamliche, Layachi,Robert, Albert
, p. 1869 - 1870 (2007/10/02)
The ring opening of α-cyano-α-hydroxymethyl epoxides by a solution of the complex Li2NiBr4 in the tetrahydrofuran leads to α-bromo-α'-hydroxy ketones which in treatment with pyridine give good yields of α-hydroxy unsaturated aldehydes.
