116210-21-0

Basic information

• Product Name: (2S,4S)-4-[3-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-propoxy]-pentan-2-ol
• CAS NO: 116210-21-0
• Molecular Weight: 248.363
• Mol File: 116210-21-0.mol

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-[3-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-propoxy]-pentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-[3-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-propoxy]-pentan-2-ol(116210-21-0)
• EPA Substance Registry System: (2S,4S)-4-[3-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-propoxy]-pentan-2-ol(116210-21-0)

Safety Data

• Hazardous Substances Data: 116210-21-0(Hazardous Substances Data)

Upstream product

• 72345-23-4 (2S,4S)-pentane-2,4-diol 
• 116185-04-7 malonedialdehyde bis[(S,S)-1,3-dimethylpropylene] acetal 

Relevant articles and documents

A Convenient Synthesis of Substituted Polyether Diols

Alkyl-substituted polyether diols (or polythioether diols), which are potential precursors to substituted crown ethers, are produced in high yield by the selective reductive cleavage of C-O bonds in bis(cyclic acetals) by borane or monochloroborane.

Substituted diether diols by ring-opening of carbocyclic and stannylene acetals

Reduction of malonaldehyde bis(ethylene and propylene acetals) with borane or monochloroborane produces diether diols 1 and 2 in high yield. Similar reduction of glyoxal his(ethylene acetals) has only limited utility for the preparation of tetrasubstituted triethylene glycols 3. Organotin chemistry is complementary: stannylene acetals prepared from disubstituted vicinal diols can be alkylated with half an equivalent of 1,2-dibromoethane to produce tetrasubstituted triethylene glycols 3, or with two equivalents of 2-chloroethanol to produce disubstituted triethylene glycols 4.