116212-46-5 Usage
Uses
Used in Pharmaceutical Research:
1,6-dihydro-6-methyl-7H-Pyrrolo[2,3-c]pyridin-7-one is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique reactivity allows for the creation of new drugs with potential therapeutic applications.
Used in Chemical Research:
1,6-dihydro-6-methyl-7H-Pyrrolo[2,3-c]pyridin-7-one is used as a research compound for studying its properties and potential applications in the field of chemistry. This includes understanding its reactivity and how it can be used to create new chemical compounds.
Used in Drug Synthesis:
1,6-dihydro-6-methyl-7H-Pyrrolo[2,3-c]pyridin-7-one is used as a building block in the synthesis of drugs, contributing to the development of new medications with improved efficacy and safety profiles. Its presence in the molecular structure of these drugs can influence their pharmacological properties and interactions with biological targets.
Check Digit Verification of cas no
The CAS Registry Mumber 116212-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,2,1 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 116212-46:
(8*1)+(7*1)+(6*6)+(5*2)+(4*1)+(3*2)+(2*4)+(1*6)=85
85 % 10 = 5
So 116212-46-5 is a valid CAS Registry Number.
116212-46-5Relevant articles and documents
Total Synthesis of Peramine
Dumas, Donald J.
, p. 4650 - 4653 (1988)
A facile synthesis of 1-oxo-2,3-disubstituted-pyrrolopyrazines, which involves the reaction of 2-(trichloroacetyl)pyrrole (3) with halomethyl ketones (to give pyrrolooxazin-1-ones) followed by successive treatment with methylamine and acid, has been developed.This methodology has been applied to the total synthesis of the insect feeding deterrent peramine (1).
BROMODOMAIN INHIBITORS
-
, (2017/11/10)
The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).
Synthesis of 2-Methylpyrrolopyrazin-1(2H)-one
Brimble, Margaret A.,Brimble, Mark T.,Hodges, Richard,Lane, Geoffrey A.
, p. 1583 - 1590 (2007/10/02)
The synthesis of 2-methylpyrrolopyrazin-1(2H)-one (2) present in the insect feeding deterrent peramine (1) through oxidation of the saturated lactam (3) is described.The preparation of the related 6-methyl-1H-pyrrolopyridin-7(6H)-one (12) trough a Lewias-acid-catalysed cyclization of the amide acetal (7) is also described.
