116270-39-4

Basic information

• Product Name: 1-Acetyl-5-broMo-4-chloro-pseudoindoxyl
• Synonyms: 1-Acetyl-5-broMo-4-chloro-pseudoindoxyl;1-Acetyl-5-broMo-4-chloro-1,2-dihydro-3H-indol-3-one;1-Acetyl-5-bromo-4-chloroindolin-3-one
• CAS NO: 116270-39-4
• Molecular Formula: C₁₀H₇BrClNO₂
• Molecular Weight: 304.52448
• Product Categories: Aromatics;Fluorescent Labels & Indicators;Indole Derivatives
• Mol File: 116270-39-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 523.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.743±0.06 g/cm3(Predicted)
• Solubility: Dichloromethane, Dimethylformamide, Ethyl Acetate
• PKA: -3.89±0.20(Predicted)
• CAS DataBase Reference: 1-Acetyl-5-broMo-4-chloro-pseudoindoxyl(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Acetyl-5-broMo-4-chloro-pseudoindoxyl(116270-39-4)
• EPA Substance Registry System: 1-Acetyl-5-broMo-4-chloro-pseudoindoxyl(116270-39-4)

Safety Data

• Hazardous Substances Data: 116270-39-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Upstream product

• 3030-06-6 1-acetyl-5-bromo-4-chloro-3-indolyl acetate 

Downstream Products

• 153248-52-3 5-bromo-4-chloro-indol-3-yl-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid) 
• 7240-90-6 5-bromo-4-chloro-3-indolyl β-D-galactopyranoside 
• 15548-60-4 (5-bromo-4-chloroindol-3-yl)-β-D-glucopyranoside 

Relevant articles and documents

Differences in reactivity of N-acetyl- and N,N-diacetylsialyl chlorides caused by their different supramolecular organization in solutions

O-Sialylation of a substituted indolin-3-one under phase-transfer catalysis conditions, which does not occur when N-acetylsialyl chloride is used, proceeds with N,N-diacetylsialyl chloride as the glycosyl donor. A study using dynamic light scattering of solutions of both sialyl chlorides under conditions close to the conditions used for glycosylation showed a difference in the correlation radii of light scattering particles in such solutions. This suggests that the introduction of an additional N-acetyl group into the sialyl chloride significantly alters the structure of the supramers of glycosyl donor, which apparently have an increased accessibility of individual molecules for the attack by a nucleophile, which increases its reactivity.