116285-37-1 Usage
Chemical Properties
Pale Yellow Solid
Uses
Different sources of media describe the Uses of 116285-37-1 differently. You can refer to the following data:
1. A metabolite of Finasteride, an inhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone
2. A metabolite of Finasteride (F342000), an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.
Check Digit Verification of cas no
The CAS Registry Mumber 116285-37-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,2,8 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 116285-37:
(8*1)+(7*1)+(6*6)+(5*2)+(4*8)+(3*5)+(2*3)+(1*7)=121
121 % 10 = 1
So 116285-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C23H34N2O4/c1-21(2,20(28)29)25-19(27)16-7-6-14-13-5-8-17-23(4,12-10-18(26)24-17)15(13)9-11-22(14,16)3/h10,12-17H,5-9,11H2,1-4H3,(H,24,26)(H,25,27)(H,28,29)/t13-,14-,15-,16+,17+,22-,23+/m0/s1
116285-37-1Relevant articles and documents
Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
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, (2008/06/13)
The compounds of formula (I) STR1 wherein R is selected from hydrogen, methyl or ethyl, and R1 is C1-12 straight or branched chain alkyl wherein one of the hydrogens is substituted by hydroxy, carboxylic acid or C1-4 alkyl ester, and A is --CH2 --CH2 or --CH=CH--, and pharmaceutical formulations of the above compounds are active as testosterone 5α-reductase inhibitors and thus are useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.