116287-43-5

Basic information

• Product Name: L-Alanine, N-(1-thioxoethyl)-, methyl ester (9CI)
• Synonyms: L-Alanine, N-(1-thioxoethyl)-, methyl ester (9CI)
• CAS NO: 116287-43-5
• Molecular Formula: C6H11NO2S
• Molecular Weight: 161.22204
• Product Categories: GLYCINESCAFFOLD
• Mol File: 116287-43-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Alanine, N-(1-thioxoethyl)-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, N-(1-thioxoethyl)-, methyl ester (9CI)(116287-43-5)
• EPA Substance Registry System: L-Alanine, N-(1-thioxoethyl)-, methyl ester (9CI)(116287-43-5)

Safety Data

• Hazardous Substances Data: 116287-43-5(Hazardous Substances Data)

Upstream product

• 3619-02-1 (S)-N-acetylalanine methyl ester 

Downstream Products

• 16816-28-7 methyl 2-[({[(benzyloxy)carbonyl]amino}acetyl)amino]propanoate 

Relevant articles and documents

A new method for peptide synthesis in the N→C direction: Amide assembly through silver-promoted reaction of thioamides

The Ag(i)-promoted coupling of amino acids and peptides with amino ester thioamides generates peptide imides without epimerisation. The peptide imides undergo regioselective hydrolysis under mild conditions to generate native peptides. This method was employed to prepare the pentapeptide thymopentin in the N→C direction, in high yield and purity.