1163-57-1Relevant academic research and scientific papers
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)
Kuduk, Scott D.,Di Marco, Christina N.,Chang, Ronald K.,DiPardo, Robert M.,Cook, Sean P.,Cato, Matthew J.,Jovanovska, Aneta,Urban, Mark O.,Leitl, Michael,Spencer, Robert H.,Kane, Stefanie A.,Bilodeau, Mark T.,Hartman, George D.,Bock, Mark G.
scheme or table, p. 2514 - 2518 (2009/12/25)
A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain.
