116308-39-5

Upstream product

• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 104-10-9 2-(4'-aminophenyl)ethyl alcohol 
• 71-36-3 butan-1-ol 

Downstream Products

• 126202-70-8 2-<4-<4-(4,4'-difluorobenzhydryl)-1-piperazinyl>phenyl>ethyl alcohol 
• 116308-40-8 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl alcohol 
• 116308-56-6 AE₀₀₄₇ 
• 126202-59-3 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[2-(4-{4-[bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-phenyl)-ethyl] ester 5-methyl ester 
• 116308-53-3 2',6'-Dimethyl-2-trifluoromethyl-1',4'-dihydro-[3,4']bipyridinyl-3',5'-dicarboxylic acid 5'-{2-[4-(4-benzhydryl-piperazin-1-yl)-phenyl]-ethyl} ester 3'-methyl ester 
• 116308-51-1 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl methyl 4-(4-cyano-2-pyridyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylate 
• 133743-70-1 2-[1-(3-Nitro-phenyl)-meth-(Z)-ylidene]-3-oxo-butyric acid 2-[4-(4-benzhydryl-piperazin-1-yl)-phenyl]-ethyl ester 
• 134364-85-5 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl 2-(4-cyano-2-pyridylmethylidene)acetoacetate 
• 116308-41-9 2-<4-(4-benzhydryl-1-piperazinyl)phenyl>ethyl acetoacetate 

Relevant academic research and scientific papers

Compound and its as L-type calcium channel blocker or/and application of acetylcholine esterase inhibitors

Disclosed in this invention are compounds and the uses as L-type calcium channel blocker and/or acetylcholinesterase inhibitor thereof. The uses of said compounds in the manufactures of a medicament for the treatment of cardiovascular diseases, apoplexy or senile dementia are also disclosed in the present invention.

Hydrogenated acridine derivative and its application

The invention relates to the field of chemical synthesis, and particularly relates to a compound with the general formula being Y-L-X and an application of the compound serving as a calcium channel blocking agent or/and an acetylcholinesterase inhibitor. The compound with the general formula being Y-L-X can be used for adjusting calcium homeostasis and treating cardiovascular diseases, stroke or dementia.

Use of dihydropyridine derivatives for the prophylaxis or treatment of cerebral circulation disorders

A cerebral hyperkinemic composition which containa as an effective ingredient at least a dihydropyridine derivative of the general formula wherein R1, R2 and R3, which are identical or different, independently represent an alkyl, a cycloalkyl or an

DIHYDROPYRIDINE DERIVATIVES AND PHARMACEUTICALS COMPOSITION THEREOF

Dihydropyridine derivatives of the formula wherein R1, R2, R3, R4, R5, A, B are defined as in the specification and nontoxic acid-addition salts thereof, have an excellent calcium blocking action (Ca-antagonist), and antihypertensive action, a platelet aggregation inhibiting action, a phosphodiesterase-inhibiting action and the like, and thus are useful as a medicine, such as a coronary vasocilator, a cerebral hyperkinemic, antihypertensive, thrombosis-preventing or treating agents, phosphodiesterase inhibitor or the like. Pharmaceutical compositions and methods of use are also disclosed