116313-73-6 Usage
General Description
TYRPHOSTIN AG 1288 is a potent inhibitor of protein tyrosine kinases, which are enzymes that play a role in the regulation of cell growth and proliferation. It has been studied for its potential therapeutic applications in cancer and inflammation due to its ability to block the activity of these kinases. Additionally, TYRPHOSTIN AG 1288 has been shown to inhibit the growth of various cancer cell lines in vitro and has exhibited anti-inflammatory effects in animal models. Its mechanism of action involves interfering with the phosphorylation of tyrosine residues in key signaling proteins, ultimately disrupting cell growth and survival pathways. Overall, TYRPHOSTIN AG 1288 shows promise as a potential therapeutic agent for cancer and inflammatory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 116313-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,1 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 116313-73:
(8*1)+(7*1)+(6*6)+(5*3)+(4*1)+(3*3)+(2*7)+(1*3)=96
96 % 10 = 6
So 116313-73-6 is a valid CAS Registry Number.
116313-73-6Relevant articles and documents
Synthesis of Some Novel Potent and Selective Catechol O-Methyltransferase Inhibitors
Baeckstroem, Reijo,Honkanen, Erkki,Pippuri, Aino,Kairisalo, Pekka,Pystynen, Jarmo,et al.
, p. 841 - 846 (2007/10/02)
A series of disubstituted catechol derivatives was synthesized and tested as potential COMT inhibitors.The most active compounds were more than 1000 times more potent (IC 50 = 3-6 nM) in vitro than the known COMT inhibitor, 3',4'-dihydroxy-2-methylpropiop