1163142-66-2Relevant articles and documents
Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACE
Wu, Yong-Jin,Zhang, Yunhui,Good, Andrew C.,Burton, Catherine R.,Toyn, Jeremy H.,Albright, Charles F.,Macor, John E.,Thompson, Lorin A.
scheme or table, p. 2654 - 2660 (2010/01/16)
A series of N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(3-methoxybenzylamino)-butan-2-yl)benzamides has been synthesized as BACE inhibitors. A variety of P2 and P3 substituents has been explored, and these efforts have culminated in the identification
