116332-50-4 Usage
Chemical Class
The compound belongs to the class of substituted pyrroles.
Structure
It consists of a 5-membered ring containing four carbon atoms and one nitrogen atom, with a trifluoromethylphenyl group attached to one of the carbon atoms.
Medicinal Chemistry Applications
2-(2-(trifluoromethyl)phenyl)-1H-pyrrole is used in the field of medicinal chemistry for the development of new drugs, particularly in the treatment of diseases such as cancer and inflammation.
Trifluoromethyl Group
The trifluoromethyl group present in the compound is known to enhance the bioactivity and metabolic stability of the molecules, making it a valuable building block for drug discovery and development.
Potential Applications
2-(2-(trifluoromethyl)phenyl)-1H-pyrrole has also been studied for its potential use in the development of agrochemicals and materials science applications.
Check Digit Verification of cas no
The CAS Registry Mumber 116332-50-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,3 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 116332-50:
(8*1)+(7*1)+(6*6)+(5*3)+(4*3)+(3*2)+(2*5)+(1*0)=94
94 % 10 = 4
So 116332-50-4 is a valid CAS Registry Number.
116332-50-4Relevant academic research and scientific papers
Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
-
, (2008/06/13)
Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picomaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.
NEW METHODS FOR THE SYNTHESIS OF 2-ARYLPYRROLES
Kruse, Chris G.,Bouw, Jan P.,Hes, Roelof van,Kuilen, Aalt van de,Hartog, Jack A. J. den
, p. 3141 - 3151 (2007/10/02)
Two short and efficient synthetic approaches for -mostly unknown- 2-arylpyrroles are presented.The key intermediates 3 are conveniently obtained from commercially available acetophenones 5 (method I) or benzoic acid derivatives 10, 11 (method II).
