116332-63-9

Basic information

• Product Name: N-Methoxy-N-Methyl-2-(trifluoroMethyl)benzaMide
• Synonyms: N-Methoxy-N-Methyl-2-(trifluoroMethyl)benzaMide
• CAS NO: 116332-63-9
• Molecular Formula: C₁₀H₁₀F₃NO₂
• Molecular Weight: 233.1871096
• Mol File: 116332-63-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Methoxy-N-Methyl-2-(trifluoroMethyl)benzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methoxy-N-Methyl-2-(trifluoroMethyl)benzaMide(116332-63-9)
• EPA Substance Registry System: N-Methoxy-N-Methyl-2-(trifluoroMethyl)benzaMide(116332-63-9)

Safety Data

• Hazardous Substances Data: 116332-63-9(Hazardous Substances Data)

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 433-97-6 2-trifluoromethylbenzoic acid 
• 201230-82-2 carbon monoxide 
• 392-83-6 o-trifluoromethylphenyl bromide 

Downstream Products

• 89638-22-2 1-(2-(trifluoromethyl)phenyl)prop-2-en-1-one 
• 1342027-89-7 2-methoxy-1-[2-(trifluoromethyl)phenyl]ethanone 

Relevant articles and documents

DOPAMINE D2 RECEPTOR LIGANDS

The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity. The present invention relates to novel compounds that modulate dopamine D2 receptors. In particular, compounds of the present invention show functional selectivity at the dopamine D2 receptors and exhibit selectivity downstream of the D2 receptors, on the 0- arrestin pathway and/or on the cAMP pathway.

Convenient method for the preparation of weinreb amides via PD-catalyzed aminocarbonylation of aryl bromides at atmospheric pressure

(Chemical Equation Presented) The direct transformation of aryl bromides into the corresponding Weinreb amides via Pd-catalyzed aminocarbonylation at atmospheric pressure is reported.