116344-11-7

Upstream product

• 37779-49-0 methyl 3-oxo-4-phenylbutanoate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 475115-41-4 5-acetyl-2-benzyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid methyl ester 
• 116344-15-1 1-phenyl-5-benzyl-4-pyrazolecarboxylic acid methyl ester 
• 80326-72-3 methyl 1-methyl-5-(phenylmethyl)-1H-pyrazole-4-carboxylate 
• 134540-98-0 5-Benzyl-isoxazole-4-carboxylic acid methyl ester 
• 116344-20-8 5-Benzyl-1-phenyl-1H-pyrazole-4-carboxylic acid 
• 116344-33-3 5-benzyl-1-methyl-1H-pyrazole-4-carboxylic acid 
• 116344-22-0 5-Benzyl-1-phenyl-1H-pyrazole 
• 107088-66-4 5-benzyl-1-methyl-1H-pyrazole 
• 121017-85-4 2-Benzyl-5-cyano-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 56304-64-4 6-benzyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 121017-79-6 2-benzyl-5-cyano-1,6-dihydro-6-oxo-3-methoxycarbonyl pyridine 
• 134541-07-4 5-Benzyl-4-isoxazolecarboxylic acid 
• 134541-13-2 2-cyano-4-phenyl-acetoacetic acid methyl ester 

Relevant academic research and scientific papers

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS

The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.