116355-89-6

Upstream product

• 109170-82-3 ethyl α-triethylsiloxypropionate 
• 102687-63-8 (E)-((3,3,3-trifluoroprop-1-en-1-yl)sulfonyl)benzene 
• 120226-10-0 (Z)-1-phenylsulfonyl-3,3,3-trifluoropropene 

Downstream Products

• 116355-90-9 2-methyl-4-phenylsulfonyl-3-trifluoromethylbutane-1,2-diol 
• 117467-32-0 C₄₄H₆₃F₃O₇S 
• 116382-58-2 2-Benzenesulfonyl-4-methyl-1-phenyl-4-(tetrahydro-pyran-2-yloxy)-3-trifluoromethyl-pentan-1-ol 
• 116382-59-3 2-Benzenesulfonyl-1-cyclohexyl-4-methyl-4-(tetrahydro-pyran-2-yloxy)-3-trifluoromethyl-pentan-1-ol 
• 116355-96-5 (S)-3-[2-[(1R,3aS)-1-((E)-(R)-5-Hydroxy-1,5-dimethyl-4-trifluoromethyl-hex-2-enyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexanol 
• 116740-30-8 2-methyl-4 phenylsulfonyl-3-trifluoromethyl-2-butanol tetrahydropyranyl ether 

Relevant academic research and scientific papers

Fluorine-containing vitamin D2 derivatives

A fluorine-containing vitamin D2 derivative represented by the following formula STR1 wherein R1 represents a methyl or trifluoromethyl group, and R2 represents a trifluoromethyl group when R1 is a methyl group,

PREPARATION OF FLUORINE-MODIFIED 25-HYDROXYVITAMIN D2: 28,28,28-TRIFLUORO-, 26,26,26,27,27,27-HEXAFLUORO- AND 28-NOR-26,26,26,27,27,27-HEXAFLUORO-25-HYDROXIVITAMIN D2

Preparations of the titled fluorinated vitamin D2 analogs (3, 4, and 5,) were efficiently achieved through reactions of the C22-aldehyde (6) with phenylsulphone derivatives (7,8 and 9).