116366-85-9Relevant articles and documents
Aminotriazine 5-HT7 antagonists
Mattson, Ronald J.,Denhart, Derek J.,Catt, John D.,Dee, Michael F.,Deskus, Jeffrey A.,Ditta, Jonathan L.,Epperson, James,Dalton King,Gao, Aiming,Poss, Michael A.,Purandare, Ashok,Tortolani, David,Zhao, Yufen,Yang, Hua,Yeola, Suresh,Palmer, Jane,Torrente, John,Stark, Arlene,Johnson, Graham
, p. 4245 - 4248 (2007/10/03)
The present studies have identified a series of aminotriazines as novel 5-HT7 receptor antagonists. Compounds 10 and 17 have high affinity for the 5-HT7 receptor and do not bind to either the 5-HT 2C or 5-HT6 re