1163711-71-4

Basic information

• Product Name: (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-oic acid 4'-nitrobenzoyloxymethyl ester
• CAS NO: 1163711-71-4
• Molecular Weight: 497.588
• Mol File: 1163711-71-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-oic acid 4'-nitrobenzoyloxymethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-oic acid 4'-nitrobenzoyloxymethyl ester(1163711-71-4)
• EPA Substance Registry System: (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-oic acid 4'-nitrobenzoyloxymethyl ester(1163711-71-4)

Safety Data

• Hazardous Substances Data: 1163711-71-4(Hazardous Substances Data)

Upstream product

• 1160958-41-7 (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-oic acid sodium salt 
• 41657-92-5 4-nitrobenzoic acid chloromethyl ester 
• 27975-19-5 isosteviol 
• 62-23-7 4-nitro-benzoic acid 

Relevant articles and documents

Synthesis and In Vivo acute anti hyperglycemic evaluation of novel isosteviol derivatives

Isosteviol is a beyerane tetracyclic diterpenoid with a large variety of biological activities. In this article, a series of novel isosteviol derivatives containing the modification of C-18 carboxyl group (5-12), C-16 carbonyl group (14-16) and heteroatom-containing frameworks fused with isosteviol structure (18-19) were synthesized and evaluated for their in vivo acute antihyperglycemeric effects. Among them, compound 8 exhibited the most potent antihyperglycemeric effects. Furthermore, primarily, structure-activity relationship (SAR) was also analyzed. The structures of all the newly synthesized compounds were determined by 1H, 13CNMR, MS, IR and elementary analysis.