1163721-90-1

Basic information

• Product Name: (Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone
• CAS NO: 1163721-90-1
• Molecular Weight: 220.228
• Mol File: 1163721-90-1.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: (Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone(1163721-90-1)
• EPA Substance Registry System: (Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone(1163721-90-1)

Safety Data

• Hazardous Substances Data: 1163721-90-1(Hazardous Substances Data)

Usage

General Description

(Z)-3-Dimethylamino-1-(3-nitro-phenyl)-propenone, also known as 3-Dimethylamino-1-(3-nitrophenyl)prop-2-en-1-one, is a chemical compound with the molecular formula C11H12N2O3. It is a yellow to brown crystalline powder with a molecular weight of 220.22 g/mol. The compound is a derivative of benzaldehyde and is used in the synthesis of various organic compounds. It is also known for its potential use as a precursor in the preparation of pharmaceuticals and agrochemicals. The compound is known to have potential biological and pharmacological activities, making it a subject of interest in the field of medicinal chemistry. However, due to its potential hazardous nature, proper care and precautions are required in handling and using this compound.

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 121-89-1 3-Nitroacetophenone 

Relevant articles and documents

Design, synthesis, in silico, and in vitro evaluation of 3-phenylpyrazole acetamide derivatives as antimycobacterial agents

Mycobacterium tuberculosis (Mtb) is one of the most dangerous pathogens affecting immunocompetent and immunocompromised patients worldwide. Novel molecules, which are efficient and can reduce the duration of therapy against drug-resistant strains, are an

COMPOUND OF 5-HYDROXYL-1,7-NAPHTHYRIDINE SUBSTITUTED BY ARYL OR HETEROARYL, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE THEREOF

Disclosed are a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, a preparation method thereof, pharmaceutical compositions and uses thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO, wherein in the formula (I), R1 and R2 are each independently hydrogen; R3 is hydrogen or C1-3 alkyl; and Ar is an aromatic ring or an heteroaromatic ring selected from a naphthalene ring, a pyridine ring, a thiophene ring, a furan ring and a substituted benzene ring.

Synthesis of Polyaromatic Rings: Rh(III)-Catalyzed [5 + 1] Annulation of Enaminones with Vinyl Esters through C-H Bond Functionalization

An expedient [5 + 1] annulation method via Rh(III)-catalyzed C-H bond functionalization of enaminones to synthesize polyaromatic rings is described. The reaction tolerates a broad range of functional groups and offers a new entry to construct polycyclic a