116386-91-5Relevant academic research and scientific papers
The Structure of Leudrin, and the Nucleophilic Substitution of its Primary Hydroxy Group by Bromine
Perold, Guido W.,Carlton, Laurence,Howard, Arthur S.,Michael, Joseph P.
, p. 881 - 884 (2007/10/02)
Leudrin (1a), present in some genera of the Proteaceae, is a pyrocatechol analogue of the phenolic spiro-bislactone leucodrin (1b).It has been characterized as its highly crystalline ar-dimethyl ether (1c).Leudrin can be re-formed from this derivative by demethylation with boron tribromide; under the conditions of the demethylation, it also undergoes unusual nucleophilic substitution to afford 11-bromo-11-deoxyleudrin (5a).The latter derivative affords leudrin after reaction with silver nitrate.
