116387-40-7 Usage
Description
METHYL 2-HYDROXY-5-IODONICOTINATE, with the molecular formula C7H7INO3, is a chemical compound derived from nicotinic acid. It is characterized by the presence of a methyl group and a hydroxyl group on the pyridine ring, along with an iodine atom at the 5th position. This unique structure endows it with versatile reactivity and makes it a valuable compound in pharmaceutical research and drug development.
Uses
Used in Pharmaceutical Research and Drug Development:
METHYL 2-HYDROXY-5-IODONICOTINATE is used as a precursor to biologically active molecules, leveraging its unique structure and reactivity to contribute to the development of new pharmaceutical agents.
Used in the Synthesis of Complex Organic Compounds:
In the field of medicinal chemistry, METHYL 2-HYDROXY-5-IODONICOTINATE serves as a building block, facilitating the creation of complex organic compounds that may have potential applications in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 116387-40-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,3,8 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 116387-40:
(8*1)+(7*1)+(6*6)+(5*3)+(4*8)+(3*7)+(2*4)+(1*0)=127
127 % 10 = 7
So 116387-40-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6INO3/c1-12-7(11)5-2-4(8)3-9-6(5)10/h2-3H,1H3,(H,9,10)
116387-40-7Relevant articles and documents
AZAQUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF
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, (2008/12/06)
Compounds of Formula (I) are useful as inhibitors of HIF prolyl hydroxylases where the definitions of the variables are provided herein.
Inhibitors of protein tyrosine phosphatase 1B
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Page/Page column 13, (2008/06/13)
Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
PYRIDONE DERIVATIVE HAVING AFFINITY FOR CANNABINOID 2-TYPE RECEPTOR
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, (2008/06/13)
It was found that the compound having a binding activity to the cannabinoid type 2 receptor represented by the formula (I): wherein R' is a group represented by the formula: -Y1-Y2-Y3Ra wherein Y1 is single bond or the like; Y2 is -C(=O)-NH- or the like; Y3 is optionally substituted aryl or the like; R2 is hydrogen or the like; R3 is alkyl or the like; R4 is alkyl or the like; R5 is optionally substituted alkyl or the like; or R3 and R4 taken together with the adjacent atom form cyclic group or the like.