1164104-62-4Relevant articles and documents
Synthesis and antioxidant properties of an unnatural plasmalogen analogue bearing a trans O-vinyl ether linkage
Lankalapalli, Ravi S.,Eckelkamp, Joseph T.,Sircar, Debajit,Ford, David A.,Subbaiah, Papasani V.,Bittman, Robert
, p. 2784 - 2787 (2009)
To assess the antioxidant behavior of trans-1, we first synthesized trans-allyl ether 4 by opening an (S)-glycildol derivative with an (E)-alk-2en-ol, and then produced the unnatural E-enol ether 1 by a stereoselective iridium(I)-catalyzed olefin isomerization. Natural cis-1 was preferentially degraded by HOCI and was more protective than trans-1 against lipid peroxidation Induced by a free-radical Initiator, demonstrating that the geometry of the 1-alkenyloxy bond participates In the antioxidant defensive role of 1.