116414-91-6

Basic information

• Product Name: 3-(tert-Butyldimethylsiloxy)butyric acid methyl ester
• Synonyms: 3-(tert-Butyldimethylsiloxy)butyric acid methyl ester
• CAS NO: 116414-91-6
• Molecular Formula: C₁₁H₂₄O₃Si
• Molecular Weight: 232.39
• Mol File: 116414-91-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(tert-Butyldimethylsiloxy)butyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(tert-Butyldimethylsiloxy)butyric acid methyl ester(116414-91-6)
• EPA Substance Registry System: 3-(tert-Butyldimethylsiloxy)butyric acid methyl ester(116414-91-6)

Safety Data

• Hazardous Substances Data: 116414-91-6(Hazardous Substances Data)

Upstream product

• 1487-49-6 3-hydroxybutyric acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 186581-53-3 diazomethane 
• 107493-76-5 tert-butyldimethylsilyl ether-β-hydroxybutyric acid 
• 81327-43-7 tert-butyldimethylsilyl ether-β-hydroxybutyric acid ethyl ester 

Downstream Products

• 1487-49-6 3-hydroxybutyric acid methyl ester 
• 89422-42-4 methyl 3-acetoxybutyrate 

Relevant articles and documents

PROCESS FOR PREPARATION OF NOVEL ANDROGEN RECEPTOR ANTAGONIST

A process for the preparation of a novel androgen receptor antagonist is provided, comprising essentially conducting cyclization reaction of a compound of formula V to obtain a compound of formula VI. This method has the advantages of easily obtainable starting material, high atomic utilization rate, mild reaction conditions, and simply post-treatment. In addition, ODM-201 and its single isomers can be synthesized directionally by controlling the stereochemistry of starting material, with the advantages of simple and controllable process and suitability for industrial production.