116441-45-3Relevant academic research and scientific papers
SYNTHESIS OF ISOQUINOLINES BEARING DIFFERENTIALLY FUNCTIONALIZED NITROGEN SUBSTITUENTS AT POSITIONS 3 AND 4 THROUGH AMINE DISPLACEMENT ON A 4-NITRO-3-(P-TOLUENESULFONYLOXY)ISOQUINOLINE
Hinkle, Jeffery S.,Lever, O. William
, p. 3391 - 3398 (2007/10/02)
A method for the synthesis of isoquinolines functionalized with differentiated nitrogen substituents at positions 3 and 4 is described.The method involves tosylation of a 3-hydroxy-4-nitroisoquinoline and subsequent tosylate displacement by amine nucleoph
