116495-45-5

Basic information

• Product Name: SARAFOTOXIN 6C, [LYS4]-
• Synonyms: [LYS4] SARAFOTOXIN S6C;SARAFOTOXIN 6C, [LYS4]-;L-Cys-L-Thr-L-Cys-L-Asn-L-Asp-L-Met-L-Thr-L-Asp-L-Glu-L-Glu-L-Cys-L-Leu-L-Asn-L-Phe-L-Cys-L-His-L-Gln-L-Asp-L-Val-L-Ile-L-Trp-OH;Sarafotoxin c【reduced】;Sarafotoxin S 6c【reduced】;[Lys4]-SRTX-c;Cys-Thr-Cys-Lys-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp [Disulfide bridges: 1–15, 3–11];Cys-Thr-Cys-Lys-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp [Disulfide bridge Cys1-15, 3-11]
• CAS NO: 116495-45-5
• Molecular Formula: C105H153N27O36S5
• Molecular Weight: 2529.82
• Mol File: 116495-45-5.mol
• Article Data: 0

Chemical Properties

• Appearance: white/solid
• Storage Temp.: −20°C
• CAS DataBase Reference: SARAFOTOXIN 6C, [LYS4]-(CAS DataBase Reference)
• NIST Chemistry Reference: SARAFOTOXIN 6C, [LYS4]-(116495-45-5)
• EPA Substance Registry System: SARAFOTOXIN 6C, [LYS4]-(116495-45-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 116495-45-5(Hazardous Substances Data)

Usage

General Description

Sarafotoxin 6C, also known as [Lys4]-sarafotoxin 6C, is a potent vasoconstrictor peptide found in the venom of the Atractaspis microlepidota snake. It belongs to the sarafotoxin family of peptides and acts on the endothelin receptor to induce constriction of blood vessels. Despite its vasoconstrictive properties, sarafotoxin 6C has also been studied for its potential in treating cardiovascular and renal disorders. However, its strong vasoconstrictive effects may also pose potential risks, making it a subject of further research and scrutiny.

InChI:InChI=1/C103H151N27O37S5/c1-10-46(6)80(100(163)123-67(103(166)167)30-50-37-109-54-19-15-14-18-52(50)54)128-99(162)79(45(4)5)127-95(158)66(36-78(144)145)120-85(148)55(20-23-71(105)133)112-90(153)61(31-51-38-108-43-110-51)117-97(160)69(41-170)125-89(152)60(29-49-16-12-11-13-17-49)116-91(154)62(32-72(106)134)118-88(151)59(28-44(2)3)115-96(159)68(40-169)124-86(149)57(22-25-75(138)139)111-84(147)56(21-24-74(136)137)113-94(157)65(35-77(142)143)122-101(164)82(48(8)132)130-87(150)58(26-27-172-9)114-93(156)64(34-76(140)141)121-92(155)63(33-73(107)135)119-98(161)70(42-171)126-102(165)81(47(7)131)129-83(146)53(104)39-168/h11-19,37-38,43-48,53,55-70,79-82,109,131-132,168-171H,10,20-36,39-42,104H2,1-9H3,(H2,105,133)(H2,106,134)(H2,107,135)(H,108,110)(H,111,147)(H,112,153)(H,113,157)(H,114,156)(H,115,159)(H,116,154)(H,117,160)(H,118,151)(H,119,161)(H,120,148)(H,121,155)(H,122,164)(H,123,163)(H,124,149)(H,125,152)(H,126,165)(H,127,158)(H,128,162)(H,129,146)(H,130,150)(H,136,137)(H,138,139)(H,140,141)(H,142,143)(H,144,145)(H