116505-67-0

Upstream product

• 115275-08-6 [(4S,5S)-5-Hydroxymethyl-2-((E)-propenyl)-[1,3]dioxolan-4-yl]-methanol 
• 115275-11-1 (S)-3-Benzyloxy-2-[((E)-but-2-enyl)oxy]-propionaldehyde 
• 115275-10-0 (2S,3S)-1-O-benzyl-2-O-<(E)-2-butenyl>threitol 
• 115275-07-5 diethyl (2R,3R)-2,3-O-((E)-crotylidene)tartrate 
• 115275-09-7 (2S,3S)-1-O-benzyl-2,3-O-<(E)-crotylidene>threitol 
• 116561-32-1 (6S,6aS,9R,9aS)-9-Benzyloxymethyl-3,3,6-trimethyl-6a,7,9,9a-tetrahydro-6H-furo[3',4':4,5]pyrano[2,3-d][1,3]dioxin-1-one 

Downstream Products

• 116505-68-1 (1R,4S,8R,9S)-1-benzyloxymethyl-7-carbomethoxy-4-methyl-4,5,8,9-tetrahydro-2,5-dioxaindane 

Relevant academic research and scientific papers

Stereo-controlled Synthesis of (-)-Ajmalicine and (-)-Tetrahydroalstotine

Stereo-controlled synthesis of the heteroyohimbine alkaloids, (-)-ajmalicine and (-)-tetrahydroalstotine, has been developed starting from diethyl L-tartrate by employing the intramolecular hetero-Diels-Alder reaction as the key step.

REMARKABLE DIASTEREOSELECTIVITY EXERTED BY DIENOPHILE CONFIGURATION IN INTRAMOLECULAR DIELS-ALDER REACTION OF ELECTRON DEFICIENT HETERODIENES: NEW CHIRAL ENTRY INTO THE SECOIRIDOID MONOTERPENES AND THE HETEROYOHIMBINE INDOLE ALKALOIDS

Reaction between the optically active glyceraldehyde (1Z) carrying Z-olefin and Meldrum's acid furnished in one step the tricyclic adduct 3 with trans 5/6 ring juncture selectively under mild conditions by spontaneous condensation followed by the intramol