116505-90-9

Upstream product

• 457890-62-9 (3R,7aS)-5-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-3-phenyl-hexahydro-pyrrolo[2,1-b]oxazole-5-carbonitrile 
• 195299-15-1 2-cyano-5-oxazolopyrrolidine 
• 37865-96-6 2-(2-bromoethyl)-2-methyl-1,3-dioxolane 

Downstream Products

• 116561-38-7 (R)-2-{(2R,5R)-2-Heptyl-5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-pyrrolidin-1-yl}-2-phenyl-ethanol 
• 116505-91-0 (R)-2-{(2S,5R)-2-Heptyl-5-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-pyrrolidin-1-yl}-2-phenyl-ethanol 
• 116830-32-1 (R)-2-{(R)-2-[2-(2-Methyl-[1,3]dioxolan-2-yl)-ethyl]-pyrrolidin-1-yl}-2-phenyl-ethanol 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS XIV: A SHORT AND EFFICIENT SYNTHESIS OF 3,5-DISUBSTITUTED PYRROLIZIDINE ALKALOIDS VIA THE CN(R,S) METHOD

The enantiospecific synthesis of the dextrorotatory enantiomer of the ant venom alkaloid 3-heptyl-5-methylpyrrolidine 11 has been achieved in four steps and 31percent overall yield from the chiral 2-cyano-5-oxazolopyrrolidine synthon 4.On the basis of pre

ASYMMETRIC SYNTHESIS XIII SYNTHESIS OF 2-ALKYLPYRROLIDINES : TOWARDS AZABICYCLIC SYSTEMS

The enantiospecific synthesis of a series of 2(S)-alkylpirrolidines from 2-cyano oxazolopyrrolidine synthon 1 is described.Two of the synthesised compunds represent key intermediates towards azabicyclic alkaloids.