116507-23-4Relevant academic research and scientific papers
New compounds in ring-opening reaction of 5-substituted epoxyisoindolines
Mance, Ana Dunja,Borovicka, Branko,Jakopcic, Kresimir,Pavlovic, Gordana,Leban, Ivan
, p. 277 - 285 (2007/10/03)
Methoxy or nitro group present in the furan ring of tertiary alkenylfurfurylamine changes the expected results of both, the intramolecular [4+2]cycloaddition and the acid catalyzed ring-opening reaction of the derived oxatricycloadduct. With a 5-methoxy group, in addition to the expected 5-methoxyisoindoline 3, the corresponding hydroxy derivative 5 was obtained. On the other hand a 5-nitro group changes the outcome of the reaction even more profoundly. Instead of the expected 5-nitroisoindoline 12, 5-nitro-substituted epoxyisoindoline 6 submitted to ring-opening reaction with the mixture of hydrobromic and acetic acid, yielded the mixture of bromo-substituted epoxy compounds 7, 8, 9 and/or bromo-substituted isoindolines 10 and 11.
Studies in the Furan Series. 23. Preparation of some New 5-Substituted furfurylallylarylamines. Influence of Substituents on the Intramolecular Diels-Alder (IMDA) Reaction
Klepo, Z.,Jakopcic, K.
, p. 1787 - 1792 (2007/10/02)
Several new N-allyl-N-(5-substituted)-2-furfuryl-p-toluidines IIIa-e with Cl, Br, I, NO2 or CH3O groups in position 5 of the furan nucleus were prepared by allylation of the corresponding secondary furfurylarylamines.Both, electron withdrawing and releasi
