116523-64-9

Upstream product

• 22080-54-2 3,5-dichloro-L-tyrosine ; hydrochloride 
• 77-76-9 2,2-dimethoxy-propane 
• 60-18-4 L-tyrosine 
• 3417-91-2 L-tyrosine methyl ester HCl 

Downstream Products

• 116523-67-2 (9S,12S,15S)-9-Benzyloxycarbonylamino-5-bromo-12-carbamoylmethyl-19,20-dichloro-7-methoxy-4,10,13-trioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3⁽²²⁾,5,17⁽²¹⁾,18-pentaene-15-carboxylic acid methyl ester 
• 116523-68-3 (9S,12S,15S)-9-Benzyloxycarbonylamino-5-bromo-12-carbamoylmethyl-19,20-dichloro-4-methoxy-10,13-dioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3⁽²²⁾,4,6,17⁽²¹⁾,18-hexaene-15-carboxylic acid methyl ester 
• 124877-25-4 (9S,12S,15S)-9-Benzyloxycarbonylamino-5-bromo-12-carbamoylmethyl-19,20-dichloro-4-hydroxy-10,13-dioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3⁽²²⁾,4,6,17⁽²¹⁾,18-hexaene-15-carboxylic acid methyl ester 
• 116523-66-1 (S)-2-{(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(3,5-dibromo-4-hydroxy-phenyl)-propionylamino]-3-carbamoyl-propionylamino}-3-(3,5-dichloro-4-hydroxy-phenyl)-propionic acid methyl ester 
• 116523-65-0 (S)-2-((S)-2-Amino-3-carbamoyl-propionylamino)-3-(3,5-dichloro-4-hydroxy-phenyl)-propionic acid methyl ester; hydrochloride 
• 107140-32-9 OF4949-III 

Relevant academic research and scientific papers

ANTI-MALIGNANT TUMOR AGENT COMPOSITION

To provide a satisfactory anticancer agent composition suppressing the growth of cancer (malignant tumor) reliably and hardly causing side effects, the present invention is directed to an anticancer agent composition including the following agents as active ingredient; a LAT1 inhibitor, and one or more agents selected from the group consisting of an alkylating agent, a platinum-based antineoplastic agent, an anti-metabolite, a topoisomerase inhibitor, an anti-microtubule polymerizing agent, a hormonal agent, an anti-microtubule depolymerizing agent, an anticancer antibiotic, and a molecular targeted agent.