116559-84-3

Upstream product

• 13482-22-9 4-hydroxycyclohexanone 
• 50-14-6 ergocalciferol 
• 70005-45-7 ergosta-5,7,22-trien-3β-ol 
• 50-14-6 Calciferol 
• 116559-87-6 epivitamin D₂ p-nitrobenzoate 
• 57-87-4 Ergosterol 
• 87407-73-6 (S)-3-[(1R,3aS)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ⁶-benzo[c]thiophen-5-ol 
• 6538-06-3 (10S)-3c-Hydroxy-10r.13t-dimethyl-17t-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(9tH.14cH)-Δ^5.7-dodecahydro-1H-cyclopenta[a]phenanthren 

Downstream Products

• 54573-75-0 1α-hydroxyergocalciferol 
• 104846-62-0 tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexyloxy}-silane 
• 50-14-6 (S)-4-Methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexanol 
• 112670-78-7 (1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-3-[2-[(R)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexanol 
• 112670-78-7 (1S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-3-[2-[(1R,3aS)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(E)-ylidene]-cyclohexanol 
• 116559-86-5 10(R),19-dihydroepivitamin D₂ 
• 116559-85-4 10(S),19-dihydroepivitamin D₂ 
• 367487-78-3 [3S-(1E,3β,5α)]-[3-fluoro-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethanol 
• 1014718-14-9 C₃₇H₅₉⁽²⁾H₆FO₂Si₂ 
• 1014718-19-4 1α-tert-butyl-dimethyl-silanyloxy-3β-fluoro-25-trimethylsilanyloxy-16-ene-20-cyclopropyl-26,27-hexadeutero-cholecalciferol 
• 199798-99-7 C₃₈H₆₅FO₂Si₂ 
• 1014717-86-2 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-93-1 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-90-8 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 

Relevant academic research and scientific papers

Provitamin D and Vitamin D Isomerizations in the Mass Spectrometer. Translational Energy Release and Collision-induced Dissociation Studies

Collision-induced dissociation mass-analysed ion kinetic energy spectrometry and translational energy release studies have established that provitamin D3 (7-dehydrocholesterol), provitamin D2 (ergostreol), vitamin D3 and vitamin D2 isomerizations in the mass spectrometer occur at the fragment ion level leading to + ions of identical structure.It was found that the reaction, +. -> +., plays a central role in these isomerizations.

Hydrotitanation-Protonation of Vitamin D2 and Its Analogues: An Efficient Method for the Preparation of 10,19-Dihydrovitamins D2 Including Dihydrotachysterol2

In this study we describe an easy and efficient method for the preparation of the known 10,19-dihydrovitamins D2 2b (DHV2-II), 2c (DHV2-IV), 3c (dihydrotachysterol2, DHT2), and the new dihydrovitamins D2 2f and 2g.This method is based on the regioselective hydrometalation reaction of vitamin D2 and its derivatives with the system Cp2TiCl2-LiAlH4 or Cp2TiCl2-Red-Al (Aldrich).Under optimal conditions, the reaction with the former of these hydrometalating systems takes place with a high degree of stereoselectivity and allows labelling at C-19.