116576-51-3Relevant academic research and scientific papers
CHROMENE S1P1 RECEPTOR ANTAGONIST
-
Page/Page column 10, (2008/12/07)
A compound of formula (I) wherein R1, R2, R3 and R4 are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing t
CHROMEN-2-ONE DERIVATIVES
-
Page/Page column 17, (2010/11/28)
A compound of formula (I), wherein R1, R2, R3, R4, R5, and ring A are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical
Pyrimidin-4-one compounds
-
, (2008/06/13)
Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, alkoxy, polyhaloalkyl, hydroxy, cyano, nitro and amino, ?or R1 with R2, R2 with R3, or R3 with R4, together with the carbon atoms carrying them, form an optionally substituted benzene ring or an optionally substituted heteroaromatic ring, X represents an oxygen atom or a methylene group, A represents an alkylene chain, ?represents an optionally substituted, unsaturated, nitrogen-containing heterocycle and R5 represents an alkyl group, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid. a medicinal products containing the same are useful as a double α2/5-HT2c antagonist.
A Novel Synthesis of 8-Allyl-7-methoxycoumarins
Mali, R. S.,Manekar, Anita R.,Tilve, S. G.
, p. 1007 (2007/10/02)
An efficient, one-step synthesis of 8-allyl-7-methoxycoumarins (3) is described starting from 2-allyloxy-4-methoxybenzaldehyde (1).In this method both Claisen rearrangement and Wittig reaction occur in tandem manner.
